Comparison of drug delivery methods: pill digestion through liver and transdermal patch absorption through skin layers
Articles

Low Dose Hormone Replacement Therapy: Why Dose, Form, and Route Change Everything

The article discusses the complexity of hormone therapy decisions for women, emphasizing the need for personalized approaches rather than a simple yes or no on hormone usage. It highlights the importance of considering dosage, delivery methods, and the specific hormones involved, particularly differentiating between types of progestogens. Local vaginal estrogen therapy is presented as a safe, effective option for many issues while cautioning against compounded bioidentical hormones. Women are encouraged to ask informed questions about their treatment options.

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Hormones

Hormone Replacement Therapy Cancer Risk: What the Headlines Got Wrong

In July 2002, a headline linked hormone replacement therapy to a 26% breast cancer risk increase, causing widespread fear among women. However, the actual numbers reveal a minimal absolute risk increase, and certain hormone therapies may even lower breast cancer risk. This miscommunication led to decades of unnecessary suffering among women, overshadowing the nuanced truth about hormone therapy.

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Articles

Allulose and GLP-1: The Sweetener That Lowers Blood Sugar

This article concludes a series about sweeteners, focusing on allulose, a rare sugar with potential benefits for lowering blood sugar. Unlike other sweeteners, allulose activates GLP-1, enhancing insulin response and glucose regulation. While human studies show promising results, more extensive research is needed to fully understand its effects and safety.

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Articles

Stevia and Gut Health: The Gentler Sweetener

Stevia is widely favored as a non-nutritive sweetener due to its plant origin and safety profile compared to other sweeteners like sucralose and saccharin. While human studies show stevia does not impair glucose tolerance, laboratory findings indicate it may affect gut bacteria. Caution is advised, with more research needed for clarity.

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Articles

Erythritol and Cardiovascular Risk: What New Research Shows

Recent research published in Nature Medicine reveals that erythritol, a common sweetener, significantly increases cardiovascular risks. A study showed that consuming 30 grams raised blood erythritol levels over a thousandfold, making platelets more reactive, leading to clotting. While regulatory bodies still consider it safe, the implications for health merit careful reconsideration.

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Articles

Sweeteners and Gut Health: What Your CGM Isn’t Telling You

Recent research challenges the perception of non-nutritive sweeteners like sucralose and saccharin as safe simply because they don’t spike blood sugar. Studies show these sweeteners can harm gut microbiota and impair glucose tolerance, while aspartame and stevia have less severe effects. Individual gut bacteria also influence responses to these substances.

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Articles

Sleeping With a Fan On: What the Doctors Left Out

The article argues against claims that sleeping with a fan is harmful, highlighting the absence of supporting research in recent articles. It emphasizes the benefits of cooler air and steady sound for deep sleep while acknowledging minor concerns about allergens and dryness. Overall, it advocates for personal experience and discernment in sleep practices.

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Articles

Pattern Detective: Learning to Notice What Your Life Keeps Repeating

The content emphasizes the importance of recognizing recurring patterns in our lives as a means to understand underlying causes of behaviors and reactions. Adopting a “Pattern Detective” mindset encourages individuals to question automatic interpretations and seek deeper insights, leading to personal growth and healing through awareness and curiosity about life’s patterns.

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Articles

The Cyclospora Parasite: Facts, Fear, and Fresh Produce

The Cyclospora parasite causes cyclosporiasis, spreading through contaminated food or water, primarily fresh produce. An outbreak has resulted in over 800 cases since May, mainly affecting Michigan. Despite fear and misinformation suggesting all produce is unsafe, health experts advise washing and cooking vegetables to reduce risk while still consuming them for their health benefits.